SAN ANTONIO — With the game on the line and a chance to take advantage of a 5-on-4 numbers game in the final minutes, the San Antonio Spurs did what they do best: pass the ball around until they find the open man for the best available shot.

That man just happened to be Manu Ginobili, who was open in the corner because Memphis’ Lance Stephenson was lying on the floor at the opposite end of the court after a collision under the San Antonio basket.

Ginobili poured in a 3-point shot, Kevin Martin followed with another a minute later, and Ginobili hit a third on the ensuing possession to allow the Spurs the cushion they needed to shrug off Memphis Grizzlies 110-104 on Friday night to remain undefeated at home.

LaMarcus Aldridge led San Antonio with 32 points and 12 rebounds as the short-handed San Antonio Spurs played just well enough to win.

The Spurs (61-11) are 37-0 at the AT&T; Center this season and have also won a franchise-best 46 straight regular-season games at home since a loss to Cleveland in March 2015.

San Antonio’s streak is the second longest in NBA history, trailing only the continuing streak by Golden State (51 games entering Friday). It’s tied with the 1995-96 Chicago Bulls for the longest home winning streak to start a season in NBA history.

With 11 games left on its schedule, San Antonio needs three more wins to break the franchise record for victories in a season, set by the 2005-06 team when it went 63-19.

The Spurs led 98-92 and were struggling to put away the Grizzlies until Ginobili’s and Martin’s 3-pointers provided some breathing room.

“The biggest play of the game was when (Stephenson) got tackled and they go down there and hit a three,” Grizzlies coach Dave Joerger said. “(San Antonio) hit three threes in a row and that was it — it was very, very frustrating.”

San Antonio played without Kawhi Leonard (right quad contusion) and Boris Diaw, Danny Green and Patty Mills (who were all held out for rest), allowing Kyle Anderson and Martin into the starting lineup.

Memphis was more of a MASH-unit than a solid NBA team, with six players — including Marc Gasol (right foot fracture), Mike Conley (left Achilles tendinitis), Zach Randolph (right ankle sprain) and Brandan Wright (right MCL sprain) — out for the game.

When the Grizzlies (41-32) lost to the Spurs 103-83 on Dec. 3, players who were responsible 75 of those points for Memphis are out, injured or no longer with the team.

“We didn’t do a very god job defensively tonight,” Spurs coach Gregg Popovich said. “We scored well enough points — we just didn’t guard. Memphis is doing a great job with all the injuries and everything. Coach Joerger and his staff have got those guys playing at a high level and they deserve a lot of credit.”

Tony Parker scored 14 points for San Antonio, Martin and Ginobili added 13 points apiece and Tim Duncan had 12.

“We didn’t follow the game plan as expected — I’m not sure if it was effort or just things that happened,” Ginobili said. “(Memphis) had a good game, but we were always a step too late. It was not a great performance. We want to improve every game and tonight we didn’t.”

JaMychal Green’s 20 points led six Memphis players in double figures. Lance Stephenson added 17 points and Matt Barnes scored 14. Chris Anderson added 13 points, Jordan Farmar had 11 and Vince Carter hit for 10 points, all in the first half, for the Grizzlies.

The Spurs led 37-23 after the first quarter (scoring the most points in any first quarter this season) and 64-51 at halftime.

Memphis outscored San Antonio 16-8 in the first four minutes of the third quarter to reduce the Spurs’ lead to 72-67 as Barnes hit a turnaround bank shot, a 3-pointer and a driving hook in the surge. San Antonio pushed the advantage back to as many as seven points before a Barnes finger roll at the buzzer put Memphis back within striking range at 88-84.

Back-to-back dunks by Green off passes from Stephenson and Barnes brought the Grizzlies back within 92-90 with 8:12 left and set the stage for a furious finish. And then the Spurs started raining shots from 3-point territory.

“That was the biggest sequence of the game,” Stephenson said of the time he was on the floor holding his ankle and Ginobili hit his big shot. “I thought I was fouled and I twisted my ankle a little, but I should have gotten up and ran back. That was one of the reasons we lost the game.”

NOTES: The Spurs won the first two games played against Memphis this season, capturing the first meeting 92-82 on Nov. 21 at the AT&T; Center and 103-83 in the second matchup on Dec. 3 at FedExForum as Spurs F Kawhi Leonard connected on a career-high seven 3-pointers. … Memphis G Ray McCallum played in 31 games with San Antonio earlier this season, averaging 2.2 points, 1.0 rebounds and 1.1 assists in 8.3 minutes. … The Spurs established an NBA season record this season by winning 54 straight games when shooting a higher field-goal percentage than their opponent. That record streak ended in a 91-89 loss at Charlotte on March 21. … Memphis has seen 27 different players log minutes this season, the highest number of players for one team in the course of a season since Dallas suited up 27 players in 1996-97. … The Grizzlies, who are in fifth place in the Western Conference standings, would become the first team in NBA history to make the NBA playoffs while using 24 or more different players in a season.

San Antonio All-Star forward Kawhi Leonard will miss his third straight game Monday night because of a right quadriceps contusion. The Spurs play the Memphis Grizzlies.

Leonard suffered the injury in a game last week against Miami.

Leonard’s quadriceps bruise isn’t considered serious, but he will have missed three straight games as the regular season winds down.

San Antonio also will be without Tim Duncan, Manu Ginobili and Tony Parker. None of the trio made the trip to Memphis as they are resting back home in San Antonio.

At 61-12, the Spurs have the second-best record in the league with only Golden State better at 66-7.

MEMPHIS, Tenn. — LaMarcus Aldridge did not travel with the Spurs to Oklahoma City for San Antonio’s game there on Saturday. Coach Gregg Popovich decreed a night of rest for the forward.

Aldridge was refreshed when returning to action Monday against the Memphis Grizzlies, scoring 31 points, grabbing 13 rebounds, and leading the Spurs to a 101-87 victory at FedExForum.

“I felt better,” Aldridge said. “More energized.”

This was Aldridge’s turn to be the front man, and he was just that, finishing 11-for-16 from the floor and 9-for-11 at the foul line. He also had three assists and two blocks in 31 minutes.

The Spurs were without Kawhi Leonard (quad contusion), and they rested Tony Parker, Tim Duncan and Manu Ginobili, just as they did against Oklahoma City.

“He steps forward every night,” guard Patty Mills (17 points with four assists off the bench) said of Aldridge. “He steps forward when no one rests as well.”

It was also a good night for San Antonio second-year man Kyle Anderson, who finished with 13 points, a season-high seven assists and a season-best four steals. Popovich has said games such as this are an opportunity for less experienced players to make their case to be a bigger part of things in the postseason.

“My whole goal for this season has been to try to get minutes in the playoffs,” Anderson said.

After losing to the Thunder, San Antonio (62-12) managed to avoid what would have been their first consecutive defeats this season.

“We just stay in the moment,” Aldridge said.

Veteran Vince Carter paced injury-depleted Memphis with 14 points off the bench. The Grizzlies (41-33) lost their third straight game while falling to 3-7 over their past 10 games. Forward JaMychal Green finished with 12 points, and Matt Barnes scored 11 points and grabbed nine rebounds.

The Grizzlies dug an early hole and trailed by as many as 16 in the first quarter when Lance Stephenson and Barnes combined for seven turnovers. Stephenson made four of the giveaways and lost the ball over and over as he tried to force drives into the paint.

“He had a tough game in general,” Grizzlies coach Dave Joerger said of Stephenson, who finished with four points on 2-for-8 shooting while compiling six turnovers. “They just sat back and waited for him because he’s going to come to you. You try to get a shot and the jumper to fall to make them play you a little bit, and it hurt them at their place (last Friday), but they were keyed into him.”

Up by eight points at halftime, the Spurs stretched the margin to 81-68 through three quarters. They led by as many as 21 points in the fourth quarter.

The Spurs shot 51.4 percent from the floor and made five of 15 from 3-point range. Memphis shot 39.8 percent from the field and hit on six of 19 from long distance (31.6 percent).

“We played good D,” Popovich said.

San Antonio had more points in the paint, 46-36, and posted a 43-39 edge on the glass.

The Spurs swept the season series from the Grizzlies 4-0.

Three of the 11 players who appeared for Memphis on Monday night are on 10-day contracts, and one, guard Jordan Farmar (nine points), started the game. No one played as many as 30 minutes.

“We tried to even the minutes out a little so everybody could find some life,” Joerger said.

Carter played 21 minutes and also spent a lot of time playing coach on the floor.

“We have a lot of guys learning in the fire,” he said.

NOTES: San Antonio F Kawhi Leonard again sat out with a right quad contusion, and Tim Duncan, Manu Ginobili and Tony Parker were all rested and didn’t make the trip to Memphis. “It’s all based on the schedule and how many minutes they’ve played,” Spurs coach Gregg Popovich said. “Three in four nights; back-to-backs — it doesn’t matter who we’re playing. We don’t pick games out.” … Memphis PF Zach Randolph missed his second straight game with a right ankle sprain. … So far, the Grizzlies have used 27 different players this season. That ties them with the 1996-97 Dallas Mavericks, who finished 24-58, for the most in league history. … Popovich, speaking on how the Grizzlies have battled despite injuries, said: “They’ve been magnificent. The coaching staff deserves huge credit for keeping them together.” … The Spurs entered Monday’s game leading the NBA in both field-goal percentage and fewest points allowed per game.